@timek1119: O ile w ogóle. Przy przepisywaniu RNA wirusowego na komórkowy nie występuje korekta:
Since RNA proofreading enzymes are absent, the RNA-dependent RNA transcriptase makes a single nucleotide insertion error roughly every 10 thousand nucleotides, which is the approximate length of the influenza vRNA. Hence, nearly every newly manufactured influenza virus will contain a mutation in its genome. The separation of the genome into eight separate segments of vRNA allows mixing (reassortment) of the genes if more than one variety of influenza virus has infected the same cell (superinfection). The resulting alteration in the genome segments packaged into viral progeny confers new behavior, sometimes the ability to infect new host species or to overcome protective immunity of host populations to its old genome (in which case it is called an antigenic shift).[https://en.wikipedia.org/wiki/Orthomyxoviridae#Replication_cycle ]
W praktyce szczepionki najlepiej działają na szczep, na który były robione. I nie „dają ochronę na jeden sezon”, tylko „są aktualizowane co roku” ;-):
Because the antigenicities of the wild viruses evolve, vaccines are reformulated annually by updating the seed strains. However, when the antigenicities of the seed strains and wild viruses do not match, vaccines fail to protect the vaccinees. In addition, even when they do match, escape mutants are often generated. [ibidem]
Podobną skuteczność do szczepionek przeciw grypie ma tzw.”procedura moskiewska” (publiczne wystąpienie jednego z rosyjskich lekarzy przy grypie H1N1 (2009-2010): „Wieczorem 2 razy po 100ml [wiadomej substancji]. Na pewno nie zaszkodzi”.).
Zdróweńko!
XD